{"id":1546,"date":"2024-06-20T09:53:23","date_gmt":"2024-06-20T07:53:23","guid":{"rendered":"https:\/\/pharmameldrugdiscovery.com\/patents\/"},"modified":"2025-09-30T13:26:48","modified_gmt":"2025-09-30T11:26:48","slug":"patents","status":"publish","type":"page","link":"https:\/\/pharmameldrugdiscovery.com\/en\/patents\/","title":{"rendered":"Patents"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1546\" class=\"elementor elementor-1546 elementor-1534\">\n\t\t\t\t\t\t<div class=\"elementor-section elementor-top-section elementor-element elementor-element-4170aa elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4170aa\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;video&quot;,&quot;background_video_link&quot;:&quot;\\\/vb\\\/patentes.mp4&quot;,&quot;background_privacy_mode&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-background-video-container elementor-hidden-mobile\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<video class=\"elementor-background-video-hosted\" role=\"presentation\" autoplay muted playsinline loop><\/video>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6d513ad6\" data-id=\"6d513ad6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-48bd079f elementor-widget__width-initial elementor-widget-tablet__width-inherit elementor-widget elementor-widget-heading\" data-id=\"48bd079f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\"><b>Patents<\/b><\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7bf8fad5 elementor-widget__width-initial elementor-widget-tablet__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"7bf8fad5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Pharmamel: Pioneers in the use of melatonin to advance <strong>innovative medical treatments<\/strong>.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-11e852bb elementor-section-height-min-height elementor-section-items-bottom elementor-section-boxed elementor-section-height-default\" data-id=\"11e852bb\" data-element_type=\"section\" data-e-type=\"section\" id=\"p1\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wide\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-10b816cf ui-col-align-left\" data-id=\"10b816cf\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-559044c1 elementor-widget elementor-widget-heading\" data-id=\"559044c1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Injectable melatonin patent for sepsis<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-745818e8 elementor-widget elementor-widget-text-editor\" data-id=\"745818e8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Preclinical studies have demonstrated the high <strong>efficacy of melatonin in parenteral administration to neutralize inflammatory activation, oxidative stress, and mitochondrial damage in sepsis models<\/strong>. This route of administration is much more effective than oral, as, in addition to the low bioavailability of oral melatonin, the first step of hepatic metabolization drastically reduces its effective circulating levels.<\/p>\n<p>This led us to formulate a melatonin injectable for intravenous administration to sepsis patients, thus enabling a clinical trial. Due to the low solubility of melatonin, we tested different solvents until we found a formulation useful for intravenous administration to patients, highly stable at room temperature, as well as at 4\u00b0C and -20\u00b0C, making it extremely useful for clinical handling.<\/p>\n<p>The patent for this injectable <b>(IPR-490 &#8211; P201430442)<\/b> has been extended to the European Union, USA, and China, and covers both the formulation and the range of effective concentrations of melatonin.<\/p>\n<p>With this injectable, we conducted a <strong>Phase II clinical trial in sepsis patients in the ICU (EudraCT 2008-006782-83)<\/strong>, obtaining excellent results as it reduces mortality and hospital stay for these patients, resulting in an improvement in the quality of life for patients and a significant saving of the costs associated with this disease.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-4ae9e7e1 ui-col-align-left\" data-id=\"4ae9e7e1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cb729af elementor-widget elementor-widget-image\" data-id=\"cb729af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/pharmameldrugdiscovery.com\/wp-content\/uploads\/elementor\/thumbs\/sepsis_-1076118448-qqigkj6ts0rhqfb2igd06n9ffawacmtbr0oqvkzoug.jpg\" title=\"Sepsis, bacteria in blood\" alt=\"Sepsis, bacteria in blood. 3D illustration showing rod-shaped bacteria with red blood cells and leukocytes\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2c2d978 elementor-section-height-min-height elementor-section-items-bottom elementor-section-boxed elementor-section-height-default\" data-id=\"2c2d978\" data-element_type=\"section\" data-e-type=\"section\" id=\"p2\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-a64304d ui-col-align-left\" data-id=\"a64304d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-73f33ff elementor-widget elementor-widget-heading\" data-id=\"73f33ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Injectable melatonin patent for viral diseases<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5509950 elementor-widget elementor-widget-text-editor\" data-id=\"5509950\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>While the previous patent covered infectious processes that can lead to sepsis, mainly of bacterial origin or chemical sepsis, we know that many cases of <b>sepsis are of viral origin<\/b> and almost any virus can cause sepsis. In fact, COVID-19 infection conditioned a state of multi-organ failure common to bacterial sepsis, which is fatal for patients in the ICU.<\/p>\n<p>Therefore, to specify the coverages of our formulation, we have filed a new patent for a melatonin injectable against viral infections.<\/p>\n<p>The patent for this injectable (<b>IPR-866 -PCT\/ES2020\/070234<\/b>) has been extended to the European Union and the USA, and covers both the formulation and the range of effective concentrations of melatonin.<\/p>\n<p>With this injectable, we conducted a <strong>Phase II clinical trial in patients infected with COVID-19 (EudraCT 2020-001808-42),<\/strong> also obtaining excellent results as it <b>reduces mortality and hospital stay for these patients<\/b>, resulting in an improvement in the quality of life for patients and a significant saving of the costs associated with this disease.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-5aa400f ui-col-align-left\" data-id=\"5aa400f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eca021c elementor-widget elementor-widget-image\" data-id=\"eca021c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/pharmameldrugdiscovery.com\/wp-content\/uploads\/elementor\/thumbs\/patente-virus-1304499871-qqigtmanud79yq3xgdr6acpu5e40ravwzzppvviop4.jpg\" title=\"Medical disposable syringe for vaccine injection and glass vial.\" alt=\"Medical disposable syringe for vaccine injection and glass vial on blue blur background.\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8efac04 elementor-section-height-min-height elementor-section-items-bottom elementor-section-boxed elementor-section-height-default\" data-id=\"8efac04\" data-element_type=\"section\" data-e-type=\"section\" id=\"p3\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wide\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-33fe757 ui-col-align-left\" data-id=\"33fe757\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e1cda8b elementor-widget elementor-widget-heading\" data-id=\"e1cda8b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Injectable melatonin patent for cancer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-65ecfb6 elementor-widget elementor-widget-text-editor\" data-id=\"65ecfb6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The <strong>antitumor potential of melatonin is very high<\/strong>, but the issue is that when administered orally, even at high doses, it does not reach sufficient concentrations inside the tumor to destroy its cells. This is because the tumor protects itself from external agents as a survival mechanism. In experimental models of human-origin head and neck cancer, we have indeed found that in cell cultures, <strong> melatonin destroys 100% of the tumor cells<\/strong>, but in vivo, its efficacy is reduced.  <\/p>\n<\/p>\n<p>Therefore, we designed a specific formulation to <strong>inject melatonin directly into the tumor in experimental models, thereby achieving complete elimination of the tumor<\/strong>.<\/p>\n<\/p>\n<p>Currently, various antitumoral injectables are being developed to directly access tumors and attempt to destroy them from the inside, as this is a more effective solution than oral administration due to the previously mentioned issue.<\/p>\n<\/p>\n<p>Our patent for this intratumoral melatonin injectable <b>(IPR-674 &#8211; P201730598) <\/b> has been extended to the European Union and USA, and covers both the formulation and the range of effective concentrations of melatonin. We are currently awaiting the completion of preclinical studies to conduct an initial Phase II clinical trial in patients. <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-6463f5c ui-col-align-left\" data-id=\"6463f5c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9f1a473 elementor-widget elementor-widget-image\" data-id=\"9f1a473\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/pharmameldrugdiscovery.com\/wp-content\/uploads\/elementor\/thumbs\/cancer-detetion-qqih453mclltxktp0fhtp74ljo8xxbnqs2meadx11k.jpg\" title=\"cancer-detetion\" alt=\"cancer-detetion\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-02d9fc6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"02d9fc6\" data-element_type=\"section\" data-e-type=\"section\" id=\"p4\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-3218665 ui-col-align-left\" data-id=\"3218665\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1b0e628 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"1b0e628\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Patented Melatonin Gel for Mucositis<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fabfa6f elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"fabfa6f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Mucositis is one of the <strong>most serious adverse effects of cancer therapy<\/strong>. It can affect the entire gastrointestinal tract, from the mouth to the anus. It manifests as ulcerations, infections, and intense pain, affecting patients&#8217; quality of life and compromising the continuity of medical treatment. Oral lesions significantly reduce the quality of life of these patients, who often require the insertion of a percutaneous endoscopic gastrostomy tube. Furthermore, mucositis lesions lead to opportunistic infections, <strong>complicate cancer treatment, and prolong hospitalization<\/strong>. Furthermore, <strong>mucositis can have a direct impact on survival rates.<\/strong><\/p><p>Therefore, <strong>we designed a patented melatonin gel formulation specifically for the treatment of mucositis.<\/strong><\/p><p>Our patent for this melatonin gel <strong>(PCT\/ES2012\/070728)<\/strong> has been extended to Europe, the United States, Canada, South America, and Asia, and covers both the formulation and the range of effective melatonin concentrations for the treatment and\/or prevention of mucositis.<\/p><p>We conducted a <strong>Phase II clinical trial (EudraCT 2015-001534-13<\/strong>) with this melatonin gel in 84 patients with <strong>head and neck cancer<\/strong> undergoing radiotherapy and chemotherapy, cisplatin, or cetuximab, in 12 hospitals in Spain<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-a0b1b0e ui-col-align-left\" data-id=\"a0b1b0e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2bf687b elementor-widget elementor-widget-image\" data-id=\"2bf687b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/pharmameldrugdiscovery.com\/wp-content\/uploads\/elementor\/thumbs\/Video-Slider-Pharmamel-Drug-Discovery-opt2_1-qox4n97bnnwzkq23sbgu3bbuxsfoptw69u9ii48hvs.jpeg\" title=\"Video-Slider-Pharmamel-Drug-Discovery-opt2_1\" alt=\"Video-Slider-Pharmamel-Drug-Discovery-opt2_1\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6d06d7b9 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6d06d7b9\" data-element_type=\"section\" data-e-type=\"section\" id=\"p5\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7b9104a1 ui-col-align-left\" data-id=\"7b9104a1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6d1e418f elementor-widget elementor-widget-heading\" data-id=\"6d1e418f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Licenses<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c798554 elementor-widget elementor-widget-text-editor\" data-id=\"c798554\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>If you are interested in exploring licensing opportunities for any of our exclusive patents in treatments for sepsis, viral diseases, or cancer, we invite you to fill out the contact form. Our team will evaluate your application and get in touch. <\/p>\n<p>Please be sure to provide detailed information about your organization and the specific purpose of your interest in the license to facilitate the evaluation process.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-23dd1c8f ui-col-align-left\" data-id=\"23dd1c8f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ad9da4f form-shadow elementor-widget elementor-widget-bdt-contact-form-7\" data-id=\"ad9da4f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"bdt-contact-form-7.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<div class=\"wpcf7 no-js\" id=\"wpcf7-f1501-o1\" lang=\"en-US\" dir=\"ltr\" data-wpcf7-id=\"1501\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/en\/wp-json\/wp\/v2\/pages\/1546#wpcf7-f1501-o1\" method=\"post\" class=\"wpcf7-form init\" aria-label=\"Contact form\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"1501\" \/><input type=\"hidden\" name=\"_wpcf7_version\" value=\"6.1.6\" \/><input type=\"hidden\" name=\"_wpcf7_locale\" value=\"en_US\" \/><input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f1501-o1\" \/><input type=\"hidden\" name=\"_wpcf7_container_post\" value=\"0\" \/><input type=\"hidden\" name=\"_wpcf7_posted_data_hash\" value=\"\" \/><input type=\"hidden\" name=\"_wpcf7_recaptcha_response\" value=\"\" \/>\n<\/fieldset>\n<h3>Contact form\n<\/h3>\n<p><label> Name <span class=\"wpcf7-form-control-wrap\" data-name=\"your-name\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" autocomplete=\"name\" aria-required=\"true\" aria-invalid=\"false\" value=\"\" type=\"text\" name=\"your-name\" \/><\/span><\/label><label> Email <span class=\"wpcf7-form-control-wrap\" data-name=\"your-email\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-email wpcf7-validates-as-required wpcf7-text wpcf7-validates-as-email\" autocomplete=\"email\" aria-required=\"true\" aria-invalid=\"false\" value=\"\" type=\"email\" name=\"your-email\" \/><\/span><\/label><label> Subject <span class=\"wpcf7-form-control-wrap\" data-name=\"your-subject\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" value=\"\" type=\"text\" name=\"your-subject\" \/><\/span><\/label><label> Message <span class=\"wpcf7-form-control-wrap\" data-name=\"your-message\"><textarea cols=\"40\" rows=\"10\" maxlength=\"2000\" class=\"wpcf7-form-control wpcf7-textarea wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" name=\"your-message\"><\/textarea><\/span> <\/label><label><span class=\"wpcf7-form-control-wrap\" data-name=\"privacy-policy\"><span class=\"wpcf7-form-control wpcf7-acceptance\"><span class=\"wpcf7-list-item\"><label><input type=\"checkbox\" name=\"privacy-policy\" value=\"1\" class=\"privacy-policy\" id=\"privacy-policy\" aria-invalid=\"false\" \/><span class=\"wpcf7-list-item-label\">I have read and accept the <a href=\"\/politica-de-privacidad\/\">privacy policy<\/a><\/span><\/label><\/span><\/span><\/span>\n\t<span class=\"wpcf7-form-control-wrap recaptcha\" data-name=\"recaptcha\"><span data-sitekey=\"6LfBh-0pAAAAAD58eyUQ9iO97dL99OkFjGQusCO-\" class=\"wpcf7-form-control wpcf7-recaptcha g-recaptcha\"><\/span>\r\n<noscript>\r\n\t<div class=\"grecaptcha-noscript\">\r\n\t\t<iframe src=\"https:\/\/www.google.com\/recaptcha\/api\/fallback?k=6LfBh-0pAAAAAD58eyUQ9iO97dL99OkFjGQusCO-\" frameborder=\"0\" scrolling=\"no\" width=\"310\" height=\"430\">\r\n\t\t<\/iframe>\r\n\t\t<textarea name=\"g-recaptcha-response\" rows=\"3\" cols=\"40\" placeholder=\"reCaptcha Response Here\">\r\n\t\t<\/textarea>\r\n\t<\/div>\r\n<\/noscript>\r\n<\/span> <input class=\"wpcf7-form-control wpcf7-submit has-spinner\" type=\"submit\" value=\"Enviar\" \/><\/label>\n<\/p><div class=\"wpcf7-response-output\" aria-hidden=\"true\"><\/div>\n<\/form>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Patents Pharmamel: Pioneers in the use of melatonin to advance innovative medical treatments. Injectable melatonin patent for sepsis Preclinical studies have demonstrated [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1546","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Pharmamel&#039;s Patents in Melatonin Treatments<\/title>\n<meta name=\"description\" content=\"Pharmamel&#039;s patents revolutionize the medical use of melatonin in treatments for sepsis, viral diseases, or cancer.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharmameldrugdiscovery.com\/en\/patents\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" 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